| Abbreviations | Meaning |
 | LIS | Locked-in Syndrome |
| LK | Lamellar Keratoplasty; Landry-Kussmaul [syndrome]; Left Kidney; Lichenoid Keratosis; Lymphokine |
| LKS | Landau-Kleffner Syndrome; Liver, Kidneys, Spleen |
| LLS | Lazy Leukocyte Syndrome |
| LMB | Laurence-Moon-Biedl [syndrome]; Left Main Bronchus; Leiomyoblastoma; Leukomethylene Blue |
| LMBB | Laurence-Moon-Bardet-Biedl [syndrome] |
| LMBS | Laurence-Moon-Biedl Syndrome |
| LMPS | Lethal Multiple Pterygium Syndrome |
| LMS | Lateral Medullary Syndrome |
| LN | Lesch-Nyhan [syndrome] |
| LNKS | Low Natural Killer Syndrome |
| LNS | Lateral Nuclear Stratum; Lesch-Nyhan Syndrome |
| LOCS | Laryngoonychocutaneous Syndrome |
| LOGIC | Laryngeal And Ocular Granulations In Children Of Indian Subcontinent [syndrome] |
| LOS | Low Cardiac Output Syndrome |
| LPHAS | Limb/pelvis-hypoplasia/aplasia Syndrome |
| LQT | Long QT [syndrome] |
| LQTS | Long QT Syndrome |
| LRS | Lateral Recess Syndrome |
| LRS | Lumboradicular Syndrome |
| LRSS | Late Respiratory Systemic Syndrome |
| LS | Leigh Syndrome |
| LS | Leriche Syndrome |
| LUFS | Luteinized Unruptured Follicle Syndrome |
| LWS | Lowry-Wood Syndrome |
| LYES | Liver Yang Exuberance Syndrome |
| LYSLK | Lymphoma Syndrome Leukemia |
| MA | Martin-Albright [syndrome] |
| MACS | Multicenter Acquired Immunodeficiency Syndrome (AIDS) Cohort Study |
| MAGIC | Mouth (or Mucosal) And Genital Ulceration With Inflamed Cartilage [syndrome] |
| MAIDS | Mouse Acquired Immunodeficiency Syndrome |
| MAIS | Manual Axial In-line Stabilization; Mild Androgen Insensitivity Syndrome |
| MAS | Macrophage Activation Syndrome |
| MAS | McCune-Albright Syndrome |
| MAS | Meconium Aspiration Syndrome |
| MAS | Milk-alkali Syndrome |
| MAS | Morgagni-Adams-Stokes [syndrome] |
| MASA | Medical Association Of South Africa; Mental Retardation-aphasia-shuffling Gait-adducted Thumbs [syndrome]; Mutant Allele Specific Amplification |
| MBPS | Megabits Per Second; Myeloblastic Syndrome |
| MBS | Marie-Bamberger Syndrome |
| MBS | Martin-Bell Syndrome; Media Broadband Service |
| MCA/MR | Multiple Congenital Anomaly/ Mental Retardation [syndrome] |
| MCAS | Middle Cerebral Artery Syndrome |
| MCES | Medical Care Evaluation Study; Multiple Cholesterol Emboli Syndrome |
| MCINS | Minimal Change Idiopathic Nephrotic Syndrome |
| MCLNS, MCLS | Mucocutaneous Lymph Node Syndrome |
| MCNS | Minimal Change Nephrotic Syndrome |
| MCS | Malignant Carcinoid Syndrome |
| MCS | Miles-Carpenter Syndrome |
| MDCR | Miller-Dieker [syndrome] Chromosome Region |
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