| Abbreviations | Meaning |
 | OCN | Oculomotor Nucleus; Oncology Certified Nurse; Osteocalcin |
| ODD | Oculodentodigital [dysplasia]; Oppositional Defiant Disorder; Osteodental Dysplasia |
| OH | Osteopathic Hospital |
| OI | Osteogenesis Imperfecta |
| OIC | Organized Indigenous Caregiving; Osteogenesis Imperfecta Congenita |
| OIF | Osteogenesis Imperfecta Foundation |
| OIF | Observed Intrinsic Frequency; Oil Immersion Field; Open Internal Fixation; Osteogenesis Imperfecta Foundation |
| OM | Osteomalacia |
| OM | Osteomyelitis |
| OM | Osteopathic Manipulation |
| OM&S | Osteopathic Medicine And Surgery |
| OMERACT | Outcome Measures In Rheumatoid Arthritis Clinical Trial |
| OMG | Object Management Group; Oligodendrocyte-myelin Glycoprotein; Osteopathic Medical School Graduate |
| OMS | Osteomyelosclerosis |
| OMT | Object Modeling Technique; Ocular Microtremor; O-methyltransferase; Ophthalmic Medical Technician Or Technologist; Osteopathic Manipulative Therapy |
| ON | Occipitonuchal; Office Nurse; Olfactory Nucleus; Onlay; Optic Nerve; Orthopedic Nurse; Osteonecrosis; Osteonectin; Overnight |
| ONFH | Osteonecrosis Of The Femoral Head |
| OO | Osteoid Osteoma |
| OP | Osteoporosis |
| OPG | Osteoprotegerin |
| OPI | Osteoblastic Proliferation Index |
| OPN | Ophthalmic Nurse; Osteopontin |
| OPS | Operations; Optical Position Sensor; Osteoporosis-pseudolipoma Syndrome; Outpatient Service; Outpatient Surgery |
| OPS | Operations; Optical Position Sensor; Optimal Parameter Search [algorithm]; Osteoporosis-pseudolipoma Syndrome; Outpatient Service; Outpatient Surgery |
| ORBD-NRC | Osteoporosis And Related Bone Diseases - National Resource Center |
| ORSA | Osteoclast Resorption Stimulating Activity |
| ORSA | Osteoclast Resorption Stimulating Activity; Oxacillin-resistant Staphylococcus Aureus |
| OS | Bone |
| OS | Osteogenic Sarcoma (context Bone Tumors) |
| OS | Osteogenic Sarcoma |
| OS | Osteosarcoma |
| OS | Osteosclerosis |
| OS-CS | Osteopathia Striata-cranial Sclerosis [syndrome] |
| OSF | Organ System Failure; Osteoclast-stimulating Factor; Outer Spiral Fiber; Overgrowth Stimulating Factor |
| OSF | Open Software Foundation; Organ System Failure; Osteoclast-stimulating Factor; Outer Spiral Fiber; Overgrowth Stimulating Factor |
| OSRC | Osteosarcoma |
| OSTEO | Osteoarthritis; Osteomyelitis; Osteopathy |
| OSTOP | Osteoporosis Society Of British Columbia |
| OV | Oculovestibular; Office Visit; Oncovirus; Osteoid Volume; Outflow Volume; Ovalbumin; Ovary; Overventilation; Ovulation |
| PACE | People With Arthritis Can Exercise [program] |
| PAO | Periacetabular Osteotomy |
| PBM | Peak Bone Mass; Peripheral Basement Membrane; Peripheral Blood Mononuclear [cell]; Placental Basement Membrane |
| PBS | Planar Bone Scan |
| PCLI | Bone Marrow Plasma Cell Labeling Index |
| PDB | Paget Disease Of Bone |
| PGAP | Pilot Geriatric Arthritis Program |
| PLO | Polycystic Lipomembranous Osteodysplasia |
| PLO-SL | Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy (Nasu-Hakola Syndrome) |
| PMO | Postmenopausal Osteoporosis; Principal Medical Officer |
| POA | Pancreatic Oncofetal Antigen; Phalangeal Osteoarthritis; Preoptic Area; Primary Optic Atrophy |
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